AVONEX PACKAGE INSERT PDF

1. Package leaflet: Information for the user. AVONEX 30 micrograms/ ml solution for Injection. (Interferon beta-1a). Pre-filled syringe. Read all of this leaflet. Package leaflet: Information for the user. AVONEX 30 micrograms/ml solution for injection in pre-filled pen. (Interferon beta-1a). Pre-filled pen. Read all of this. Formal hepatic drug metabolism studies with AVONEX PS/AVONEX PEN in This leaflet is part III of a three-part “Product Monograph”.

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It does not take the place of talking to your specialist, doctor or pharmacist. If needed, expel some product to obtain desired dose. Premedication with acetaminophen or ibuprofen and administration of interferon beta-1a at bedtime may lessen the severity of flu-like symptoms. Moderate Ocrelizumab has not been studied in combination with other immunosuppressive or immune modulating therapies used for the treatment of multiple sclerosis, such as interferon beta-1a or interferon beta-1b.

Interferon beta is produced by various cells including fibroblasts and macrophages, and has both antiviral and immune regulatory activities. Do not place in the freezer or freezing compartment of a refrigerator. Inject subcutaneously using a dart-like motion into the outer surface of the upper arm, abdomen, thigh, or buttock.

Patients with chronic, cirrhotic HCV co-infected with HIV receiving antiretroviral agents and alpha interferons insedt to be at increased risk for hepatic decompensation e. Do not re-use needles, syringes, pre-filled syringes, titration devices, or autoinjectors.

Remove 1 Administration Dose Pack from refrigerator about 30 minutes prior to use to warm to room temperature. The pre-filled syringe cap of interferon beta-1a contains natural rubber latexwhich may cause hypersensitivity reactions in those patients with latex hypersensitivity. A seizure, fit lackage convulsion. Local skin reactions may be reduced by applying ice or a lnsert compress to the site after injection.

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The plastic needle cover will pop off after the injector shield has been fully extended. Hold Pen at 90 degree angle to the injection site. Recovery may be complete or incomplete. However, a small number of nursing mothers receiving interferon beta-1a reported no adverse effects in their partially breast-fed infants, and the amount of interferon beta-1a excreted into breast milk appeared to be insignificant.

Push down on blue activation button with thumb and count to Be sure to push the plunger all the way down until touches the collar. Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition.

You should always talk to your doctor if you are feeling depressed, pqckage having suicidal thoughts. Additionally, interferon beta-1a should not be used in patients with hamster protein hypersensitivity. Discontinuation of interferon therapy is recommended. Underlying chronic HCV infection enhances the risk of developing liver enzyme elevations in patients receiving nevirapine. Discard any unused solution.

Avonex CMI | Mobile

Doses of 60 mcg IM once weekly do not provide any additional benefits versus the 30 mcg dose. Major Patients receiving stavudine with interferons with or without ribavirin should be closely monitored for treatment-associated toxicities, especially hepatic decompensation. If you are not sure whether you should use this medicine, talk to your doctor or pharmacist.

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We do not record any personal information entered above. Guidelines recommend the use of a peginterferon product plus ribavirin as part inseert a combination regimen depending on patient factors and genotype.

Hepatic injury including elevated hepatic enzymes, jaundice, and hepatitis, some of pacage have been severe, has been reported in patients receiving interferon beta-1a see Adverse Reactions.

Do not expose to high temperatures.

Avonex is administered as an IM injection. Do not use a double dose to make up for the dose that you missed. Muscle stiffness or spasms. Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing, swelling of the face, lips, tongue or other parts of the body, rash, itching or hives on the skin. If it is incomplete there is ‘progression of disability’.

Reconstitution and Administration of Avonex lyophilized powder: Cobicistat; Elvitegravir; Emtricitabine; Tenofovir Alafenamide: Do not take more than the recommended dose. Do not use heat sources heater or hot water to warm it. Major Natalizumab should be used with caution with interferon beta because of the potential for increased risk of progressive multifocal leukoencephalopathy PML and other serious infections with combined use.

Talk about this with your doctor or pharmacist if you want more information. Firmly push the body of the pen down against the thigh to release the safety lock.